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Boston MA Full Time Posted: Wednesday, 14 March 2018
Applicants must be eligible to work in the specified location
Requisition ID: ADM009328

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the Spark that fuels innovation and inventiveness; this is the space where Merck has codified its Legacy for over a century. Merck's success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world's premier, most research-intensive biopharmaceutical company. Today, we're doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck's leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

The Merck Early DiscoveryNeuroscience team is seeking a motivated andtechnically skilled student majoring in the Biological sciences or pharmacy. The student should have strong interest in neuroscienceand learning about CNS drug discovery. Successfulcandidates will be able to work independently, and will also be expected toproactively collaborate with colleagues. Primary responsibilities include contributing to the execution of invitro experiments including establishing in vitro cell-based model systems,development of immunoassays and performing biochemical and immunohistochemical analysisof tissues to support the identification and validation of novel targets totreat CNS diseases. The candidate will be an active participant in the positiveand critical scientific dialogue that supports our mission of targetidentification and validation.

Theresponsibilities of the Early Discovery Neuroscience team member include:

  • Design, execute, interpret andreport in vitro and in vivo experiments.
  • Assist in developing, executing, andtroubleshooting new cell assays, protocols and imaging methods
  • Conducting experiments to determineefficacy of test compounds, establish dose-response andpharmacokinetic/pharmacodynamic relationships, investigate biomarker responsesand target engagement or modulation in vivo
  • Support characterization andvalidation of antibody activity in cell based and in vivo models
  • Communication of data clearly andconcisely to teams and stakeholders
  • Monitor, review and criticallyinterpret published work to guide their own research
  • Collaborate with members from otherfunctional areas, including medicinal chemistry, in vivo and in vitropharmacology and genetics


  • Candidates must be actively working towards a degree inBiological Sciences or a related discipline such as chemistry, pharmacy orhealth-related field
Required Experience:
  • Candidates must be available to work Full time for 6 months beginning in July of 2018
  • Candidates must have some experience with in vivo (mouse) techniques,including stereotaxic surgery, handling, dosing
  • Candidates must have some experience with basic lab procedures:pipetting, solution preparation, plate assays
  • Candidates must have the ability to perform accurate dataanalysis
Preferred Experience:
  • Strong desire todevelop knowledge of neuroscience drug discovery
  • Neuroscienceclass work preferred
  • Preferredexperience with basic mammalian cell culture, ie, transfections, primaryneurons
  • Excellentoral and written communication skills, including preparation of lab reports andpresentations. Strong attention to detail
  • Experiencewith rodent behavior, animal handling, dosing procedures a plus

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we're inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to (see below) .

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

Visa sponsorship is not available for this position.

For more information about personal rights under Equal Employment Opportunity, visit:

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FTP 2018

Job: Administrative Svcs Generic
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Employee Status: Temporary
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Company Trade Name: Merck

Boston MA, United States of America
3/14/2018 12:07:27 PM

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